FEATURED STUDENT PROJECT: Sophia Zega

What are the molecular processes distinguishing cell regeneration from cell development? Using zebrafish as a model organism, Sophia Zega studies one facet of this question by investigating the role of FAT2 protein in initial hair cell development, and in hair cell regeneration. Based on previous evidence we know FAT2 levels increase following hair cell ablation in preparation for regeneration. Sophia performs a knock down of FAT2 in zebrafish larvae, and then stains hair cells with dyes binding to actin and microtubules, to see how the FAT2 gene is important for hair cell development and regeneration.