Biz sitting at her bench, with a microphotograph of fluorescent beads, and a petri dish of fluorescent culture

Student Research: Biz Osborne-Schwartz

In her senior project, Biz Osborne-Schwartz’ 17 sought to improve oral rehydration therapies (ORT) for cholera patients. Working with her advisor, Professor Brooke Jude, Biz developed a protocol to study the attachment of Vibrio cholerae to chitin (a stand-in for a human intestinal cell) and other carbohydrates. This new protocol allowed her to test if adding a certain type of chemical compounds, called enzyme resistant carbohydrates, to ORT could decrease the number of bacteria in a patient infected with cholera. Biz observed a decrease in Vibrio cholerae attached to chitin beads when incubated in ORT with enzyme resistant starches, which means that more complex ORT are promising for cholera patients!