What are the molecular processes distinguishing cell regeneration from cell development? Using zebrafish as a model organism, Sophia Zega studies one facet of this question by investigating the role of FAT2 protein in initial hair cell development, and in hair cell regeneration. Based on previous evidence we know FAT2 levels increase following hair cell ablation in preparation for regeneration. Sophia performs a knock down of FAT2 in zebrafish larvae, and then stains hair cells with dyes binding to actin and microtubules, to see how the FAT2 gene is important for hair cell development and regeneration.
In this study, Bruce Robertson and coauthors tested whether non-native plant species may cause problems to Veeries when birds try to build nests in these plants. It appears that Veeries do indeed prefer non-native plants to native ones, but fortunately in this case their preference is not maladaptive, as non-native plants still provide enough protection and concealment for the nests.
Brains consist of many cells called neurons: billions of them in a human brain, and hundreds of thousands in the brain of a small fish or a frog tadpole. Many of these neurons are very much alike, and work together to process information in the brain. Yet while they are similar, they are not exactly identical. By looking at how individual neurons within a specific type differ from each other, it is possible to understand more about how they work together.
We have now compared the properties of the neurons in a part of the brain of a developing frog tadpole that processes sensory information. These neurons appear relatively similar to each other in young tadpoles, yet as the tadpoles grow and their brains become more elaborate the neurons become increasingly diverse, and their properties become more unique and nuanced.
Ciarleglio, C. M., Khakhalin, A. S., Wang, A. F., Constantino, A. C., Yip, S. P., & Aizenman, C. D. (2015). Multivariate analysis of electrophysiological diversity of Xenopus visual neurons during development and plasticity. eLife,4, e11351.
(by Olivia Williams)
Each spring, glass eels make their way from the Sargasso Sea to the Hudson River and then swim up various tributaries, including the Saw Kill. The New York DEC organizes the Eel Project where they set up eel nets across the Hudson River tributaries to track and count eel populations and migrations. The Bard College Field Station is one of the many locations that collects the data, and on March 28 we will be installing the eel net! For the next two months or so, we are looking for volunteers to come down to the field station and record data. Experience is not necessary as we will have trainings for the first week, and there will always be an experienced eel monitor with each group! To sign up, e-mail Olivia Williams.
David Hendler in interested in wildlife conservation. In his senior project he is trying to develop methodologies for surveying wildlife corridors in fragmented forest habitat. To study this question, David placed dozens of automatic wildlife cameras in the woods around the Town of Red Hook. Working under supervision of professors Felicia Keesing and Bruce Robertson, he collected thousands of photographs of various mammals, and analyzed them, to check whether animal diversity is different in in wildlife corridors compared to the larger habitats they connect.
On a picture: a collage of several photos, one showing a coyote, and another one with some deer.
For her senior project, Alessia Zambrano characterized biofilms produced by a bacterium Janthinobacterium lividum: a strain isolated from the Hudson River Valley area that plays an essential role in aquatic health and community diversity. Alessia took three-dimensional images of the biofilm using an atomic force microscope. These 3D reconstructions for the first time provide a detailed picture of the shape, size, and surface topography of individual cells of this bacterial strain.
Biology seminar schedule
- 2/4 Information Session
- 2/11 Nsikan Akpan; NPR newshour
- 2/18 Mirkka Sarparanta; Memorial Sloan Kettering Cancer Center
- 2/25 Rahul Satija; NYU
- 3/3 Dorothy Peteet; Lamont-Doherty Observatory
- 3/10 Christine Brown; NCSU
- 3/17 Paul Turner; Yale
- 3/24 spring recess
- 3/31 Gautam Sethi; Bard
- 4/7 Jean-Sebastien Moore; Université Laval
- 4/14 Moderation Day, no seminar
- 4/21 Sarah Dunphy-Lelii; Bard
- 4/28 Jane Carlton; NYU
- 5/5 Student Talk I
- 5/12 Betul Kacar; Harvard
- 5/19 Student Talk II
A publication by Brooke and Craig Jude in JMBE is focused on building microbial fuel cells (bacterially powered batteries) in the college and local school classroom! These microbial fuel cells serve as lab projects in Brooke Jude’s BIO145 Environmental Microbiology course and are also constructed when local 8th grade classes visit Bard through Center For Civic Engagement (CCE) sponsored events (that are taught by Bard students!)
Citation and full-text link: Jude CD, Jude BA. Powerful Soil: Utilizing Microbial Fuel Cell Construction and Design in an Introductory Biology Course. J Microbiol Biol Educ. 2015 Dec 1;16(2):286-8. doi: 10.1128/jmbe.v16i2.934. eCollection 2015 Dec.
Nsikan transferred to Bard from Bard College at Simon’s Rock after his sophomore year. In the summer of 2005, he did research on neuroendocrinology with Bruce S. McEwen of Rockefeller University. For his senior project, he did research on NMDA receptors in zebrafish. He was a research assistant in the Department of Pathology at Tufts Medical School studying Trypanosoma cruzi, the causative agent of Chagas disease. In 2012, he obtained his Ph.D. from Columbia University for studies of drug treatments for stroke victims. He is now a medical reporter who specializes in infectious diseases and mental health. His writing has been featured in Medical Daily (International Business Times), Scientific American, Science nagazine, NatureNews, and The Scientist magazine.
The rise of antibiotic resistance found in microbial pathogens was driven by the use and misuse of antibiotics in modern medicine and agriculture. However, the extent to which antibiotic pollution impacted microbial communities found in soil and remote environments is unclear. Using a metagenomic approach to investigate microbes found in the Canadian high Arctic, Dr. Perron and colleagues found common microbial pathogens resistant to multiple antibiotics among these remote Arctic microbial communities. Dr. Perron’s team also showed that although antibiotic-resistant bacteria were also found in 5,000 years old permafrost soils, these bacteria did not show resistance profiles normally associated with infection.
Citation: Perron GG, Whyte L, Turnbaugh PJ, Goordial J, Hanage WP, Dantas G, & Desai MM. (2015). Functional characterization of bacteria isolated from ancient Arctic soil exposes diverse resistance mechanisms to modern antibiotics. PLoS ONE. 10: e0069533