David Hendler in interested in wildlife conservation. In his senior project he is trying to develop methodologies for surveying wildlife corridors in fragmented forest habitat. To study this question, David placed dozens of automatic wildlife cameras in the woods around the Town of Red Hook. Working under supervision of professors Felicia Keesing and Bruce Robertson, he collected thousands of photographs of various mammals, and analyzed them, to check whether animal diversity is different in in wildlife corridors compared to the larger habitats they connect.
On a picture: a collage of several photos, one showing a coyote, and another one with some deer.
For her senior project, Alessia Zambrano characterized biofilms produced by a bacterium Janthinobacterium lividum: a strain isolated from the Hudson River Valley area that plays an essential role in aquatic health and community diversity. Alessia took three-dimensional images of the biofilm using an atomic force microscope. These 3D reconstructions for the first time provide a detailed picture of the shape, size, and surface topography of individual cells of this bacterial strain.
A publication by Brooke and Craig Jude in JMBE is focused on building microbial fuel cells (bacterially powered batteries) in the college and local school classroom! These microbial fuel cells serve as lab projects in Brooke Jude’s BIO145 Environmental Microbiology course and are also constructed when local 8th grade classes visit Bard through Center For Civic Engagement (CCE) sponsored events (that are taught by Bard students!)
Citation and full-text link: Jude CD, Jude BA. Powerful Soil: Utilizing Microbial Fuel Cell Construction and Design in an Introductory Biology Course. J Microbiol Biol Educ. 2015 Dec 1;16(2):286-8. doi: 10.1128/jmbe.v16i2.934. eCollection 2015 Dec.
Nsikan transferred to Bard from Bard College at Simon’s Rock after his sophomore year. In the summer of 2005, he did research on neuroendocrinology with Bruce S. McEwen of Rockefeller University. For his senior project, he did research on NMDA receptors in zebrafish. He was a research assistant in the Department of Pathology at Tufts Medical School studying Trypanosoma cruzi, the causative agent of Chagas disease. In 2012, he obtained his Ph.D. from Columbia University for studies of drug treatments for stroke victims. He is now a medical reporter who specializes in infectious diseases and mental health. His writing has been featured in Medical Daily (International Business Times), Scientific American, Science nagazine, NatureNews, and The Scientist magazine.
The rise of antibiotic resistance found in microbial pathogens was driven by the use and misuse of antibiotics in modern medicine and agriculture. However, the extent to which antibiotic pollution impacted microbial communities found in soil and remote environments is unclear. Using a metagenomic approach to investigate microbes found in the Canadian high Arctic, Dr. Perron and colleagues found common microbial pathogens resistant to multiple antibiotics among these remote Arctic microbial communities. Dr. Perron’s team also showed that although antibiotic-resistant bacteria were also found in 5,000 years old permafrost soils, these bacteria did not show resistance profiles normally associated with infection.
Citation: Perron GG, Whyte L, Turnbaugh PJ, Goordial J, Hanage WP, Dantas G, & Desai MM. (2015). Functional characterization of bacteria isolated from ancient Arctic soil exposes diverse resistance mechanisms to modern antibiotics. PLoS ONE. 10: e0069533
Parris Humphrey ’06 transferred to Bard. In his junior year, he traveled to Kenya with Dr. Felicia Keesing to study why the sandflies that transmit leishmaniasis, a tropical disease, are more abundant in areas without large herbivores like giraffes, zebras, and elephants. For his senior project, he figured out that deer can clear blacklegged ticks of the bacterium that causes Lyme disease. After graduation, he worked as a research assistant studying the molecular ecology of disease at the U. of Pennsylvania with Professor Dustin Brisson. As of early 2016 Parris is about to get a Ph.D. from the University of Arizona, where he studies disease ecology and evolution.
We are pleased to announce that the new confocal microscope is actually up and running for quite some time already! Great news for Bard Biology Program!
On the photo: Clara Woolner is visualizing reticulospinal neurons in the brain of Xenopus tadpoles.
Batrachochytrium dendrobatidis (Bd) is a deadly pathogen of many species of amphibians. One of the most promising ways to combat its spread is to expose Bd zoospores to a purple pigment, violacein, which can kill Bd. Working with Professor Brooke Jude, Abby Soussan is determining whether Bd zoospores can sense and move away from the pigment, which would seriously inhibit the effectiveness of this potential treatment.
In this paper a team of neuroscientists from Brown University and Bard College show that Xenopus tadpoles can be used as an experimental model to study molecular mechanisms of autism spectrum disorders (ASD). We used a chemical called valproic acid that is known to increase the incidence of ASD in humans, and studied its action on tadpoles. It turned out that tadpoles exposed to valproic acid developed abnormalities that are surprisingly reminiscent of that in ASD-affected humans. It suggests that tadpoles can indeed be used to study the original molecular reasons that make “autistic brains” develop differently than “normal brains”.
Citation: James EJ, Gu J, Ramirez-Vizcarrondo CM, Hasan M, Truszkowski TL, Tan Y, Oupravanh PM, Khakhalin AS, Aizenman CD. (2015). Valproate-Induced Neurodevelopmental Deficits in Xenopus laevis Tadpoles. The Journal of Neuroscience, 35(7), 3218-3229.
Free text at PubMed Central.
Press-release from Brown University.